Specialty Syringe Filters

 HPLC Certified

High quality and cost effective syringe filters are
available in a broad range of membrane materials
with sterile and non-sterile packaging options.

Features

• Disposable
• Luer-Lok™ and pressure fitting
• Ultrasonically bonded for reliability
• Filter media type clearly inscribed on barrel
• Excellent unit-to-unit and lot-to-lot reproducibility and consistency
• High purity virgin polypropylene housing, no dyes or pigments added
• Every unit type is available as an individually wrapped gamma sterilized pack
• Unique concentric funnel shaped barrel increases volume and decreases back pressure

Product Selection Guide

Evaluate sample:

• Determine chemical compatibility, volume and need for prefiltration

Determine level of prefiltration necessary:

• In filter unit vs. prefilter unit in series for coarse precipitants.

Choose filter media type:

• Aqueous: Nylon, MCE, CA
• Non-polar: Nylon, PTFE, PVDF
• Protein: PVDF, PES

Choose barrel diameter:

• 10 mL: 13 mm diameter
• 100 mL: 25 mm diameter

Choose initial or secondary retention target:

• 0.45 µm or 0.20 µm

Download product literature now!

Check out our newest product - HydroBlokr™ serological pipette device filter

Filter Material Specs

Filtration Media / Application Guide (hydrophobic or hydrophilic)
Glass microfiber filter media - prefilter versions available in all variations except MultiDensity which includes prefilter

Mixed Cellulose Esters (MCE) - Hydrophilic

• This membrane is recommended for all filtrations in aqueous or polar media, bacteria filtration
• Ideal when maximum protein recovery in filtrate is crucial
• Used for filtration and inspection of gas, oil and alcohol particulate and bacteria
• Combined with glass microfiber prefilter, ideal for tissue culture media and sensitive biological samples
• Sample filtration - prefilter increases yield

Cellulose acetate (CA) - Hydrophilic

• Very low binding capacity for proteins.
• Material is nitrate-free making it suitable for groundwater & EPA ASTM’s.
• For filtration under sterile conditions
• Filtration and clarification of biological fluids, sterilization of media additives and serum
• Sample preparation of aqueous solutions
• For applications requiring maximum sample recovery
• Sample preparation of protein-based HPLC solutions
• Designed to sterilize and remove particulates from even the most viscous proteinaceous samples
• Filtration of tissues culture media with glass fiber prefilter

Polyamide/Nylon (PA) - Hydrophilic

• Hydrophilic material; it is recommended for filtration of aqueous or organic/aqueous medium polar liquids.
• Commonly used for general laboratory filtration and filtration of HPLC and GC samples prior to injection
• Filtration of aqueous and organic-aqueous polar medium liquids
• Dissolution sample analysis
• Suitable for use with high pH samples
• Since it binds proteins it is NOT suitable for protein recovery applications
• With microfiber prefilter higher absorption capacity for contamination

Polyethersulfone (PES) - Hydrophilic

• High filtration flow rates
• An inherently low affinity for proteins.
• Low extractables
• Introduction of additives into tissue culture vessel.
• Certified for Ion Chromatography
• Final filtration of bacteriophage and infusion solutions
• Tissue culture, proteins, buffer and nucleic acids filtration
• Ideal for applications requiring maximum sample recovery
• Filter hybridization solutions and probe to reduce backgrounds
• Food, beverages and ultra pure water final filtration
• Sterile product individually blister packed

Polyvinylidene difluoride (PVDF) - Hydrophobic

• This membrane features a stability and hydrophobic interactions similar to PTFE.
• Recommended especially for filtration of water-soluble oligomers and polymers, e.g. protein solutions.
• Can also be used for the filtration of hydrophobic substances in different organic solvents.

Polytetrafluoroethylene (PTFE) - Hydrophilic or Hydrophobic

• PTFE membranes are inherently hydrophobic; they are ideal for the filtration of nonpolar liquids and gases.
• Very resistant to solvents as well as acids or bases.
• Can be made more hydrophilic by flushing with alcohol, followed by water
• Used for filtering and de-gassing chromatography solvents
• Permits optimal utilization of small sample volumes
• Excellent chemical compatibility for filtering harsh chemicals that destroy other membrane materials
• Moisture barrier for venting applications and vacuum pump line protection
• Ideal for aerosol sampling
• Filter viscous organic based HPLC samples
• After pre-wetting with alcohol, may be used for fine particle removal of aqueous and mild organic solutions in Ion Chromatography

Glass Fiber Prefilters

• For viscose solutions or for turbid liquids
• Glass microfiber prefilter raises absorption capacity and loading
• Ideal for use as a prefilter in series with other syringe filters
• Glass microfiber filter media enclosed in this series is binderless 1.0µm retention
• Reduces clogging of the membrane, so ideal as a prefilter to increase throughput and flow rate
• Ideal for dissolution testing and general filtration
• Applicable to all membrane types, allowing higher flow rates
• Good compatibility with strong acids, bases and organic solvents
• Similar in composition to I.W. Tremont binderless borosilicate glass microfiber media available as disks and sheets

Polypropylene (PP)

• The polypropylene membrane is resistant to many organic solvents and slightly hydrophobic
•  Useful for aqueous and organic solutions
• Low non-specific protein binding

MultiDensity Nano Glass Micro Fiber 

• Multi Density Glass Microfiber with several layers of density that speeds and optimizes filtration
• Bridges the gap between macro and micro analytical filtration
• Media includes multi pre-filtration stages and final retention stage down to 0.5um
• Built-in prefilter captures particulate from >300μm and binds typically difficult to filter substances without clogging such as lipids (natural oils and waxes), petrochemical oils, tars, cellular matter and proteins.

Nano Glass Micro Fiber A83

• Nano-scale glass microfiber has the loading capacity of a binderless glass microfiber filter with the tightly regulated pore size of a microfiltration membrane
• This specialty grade has a particle retention of 0.5µm
• A83 has >20x loading capacity of an equivalent porosity MCE or CN membrane and >15x the flow rate
• Chemically inert, pure binderless borosilicate glass with no sizing additives or other surfactants
• Low background noise in LC/GC/MS and very low extractables in presence of aggressive solvents
• Smooth sheath of the glass fiber allows tight consolidation into a highly retentive filter mat
• High protein affinity and highly washable for separation recovery
• Chemically stable in presence of all acids with exception of hydrofluoric acid

Fibrous Cellulose Acetate

• Fibrous Cellulose Acetate depth filter media demonstrates a high surface area to mass ratio and natural high loading capacity
• Unique fibrous material demonstrates similar advantages as its Cellulose Acetate surface membrane counterparts such as surface bonding, high purity and biocompatibility
• Fibrous media has an inherent charge that initially has high protein binding but upon loading, releases easily and completely for high recovery rates

Tri-Layer PP/GF Prefilters with Nylon, PVDF or PTFE Membrane

• A tri-layer filter with both a glass microfiber and polypropylene prefilter that raises absorption capacity and loading of a choice of Nylon PTFE or PVDF membrane
• Designed for viscous solutions or for turbid liquids

Syringe Filters Products

Material Classifications>

Polyamide/Nylon (PA) – Hydrophilic

Polytetrafluoroethylene (PTFE) – Hydrophilic or Hydrophobic

Polyvinylidene difluoride (PVDF) – Hydrophobic

Polyethersulfone (PES) – Hydrophilic

Cellulose Acetate (CA) – Hydrophilic

Mixed Cellulose Esters (MCE)-Hydrophilic

Prefilters, Glass Microfiber

Polypropylene (PP)

MultiDensity Nano Glass Microfiber

Nano Microfiber

Cellulose Acetate Fibrous

Tri-Layer PP/GF with  Nylon, PVDF, PTFE

Syringe Filter Capabilities

Beyond the extensive product selection found within our standard syringe filter list, we offer OEM capabilities for engineering, molding and insertion of many additional membrane and membrane/pre-filter options.   We can work with most of our own membrane and specialty materials as well as convert your supplied product.  Please contact us for full engineering capabilities as well as process flow and project management services in this field.

• Filter insertion in clean room by manual as well as fully automated means.
• Molding in place, over molding and support structure molding of fragile media.
• Ultrasonic welding of barrel structure for increased leak / burst resistance.
• Multi-process mold extensions for inclusion of single or multi-level prefiltration media.
• Digital variable print capabilities along arc on barrel face for identification purposes.
• Blister packing for EO and gamma sterilization.
• Pure virgin PP, verified by HPLC against U/L extractables.

13mm diameter syringe filter:

• Filter Ø: 13 mm
• Filtration area: 1.09 mm²
• Housing material: polypropylene
• Holdup volume: <20 µl
• Sample volume: <10 ml
• Maximum Operating Temperature: 130°C (Housing only, also dependent on membrane)
• Maximum Operating Pressure: 87 psi (Housing only, also dependent on membrane)
• Inlet: Luer lock female
• Outlet: Luer slip male

17mm diameter syringe filter:

• Filter Ø: 17 mm
• Filtration area: 1.65 cm²
• Housing material: polypropylene
• Holdup volume: <20 µl
• Sample volume: <20 ml
• Max. housing pressure: 8 bar
• Maximum Operating Temperature: 80°C (Housing only, also dependent on membrane)
• Maximum Operating Pressure: 87 psi (Housing only, also dependent on membrane)
• Inlet: Luer lock female
• Outlet: Luer slip male
• Biological Safety: Filter medium and housing material meet USP XXII Class VI,121 ℃

25mm diameter syringe filter:

• Filter Ø: 25 mm
• Filtration area: 4.08 cm²
• Housing material: polypropylene
• Holdup volume: <100 µl
• Sample volume: <100 ml
• Maximum Operating Temperature: 130°C (Housing only, also dependent on membrane)
• Maximum Operating Pressure: 87 psi (Housing only, also dependent on membrane)
• Inlet: Luer lock female
• Outlet: Luer slip male
• Biological Safety: Filter medium and housing material meet USP XXII Class VI,121 ℃

30mm diameter syringe filter:

• Filtration area: 4.9cm²
• Housing material: polypropylene
• Holdup volume: <100 µl
• Sample volume: <120 ml
• Max. housing pressure: 8 bar
• Maximum Operating Temperature: 80°C (Housing only, also dependent on membrane)
• Maximum Operating Pressure: 87 psi (Housing only, also dependent on membrane)
• Inlet: Luer lock female
• Outlet: Luer slip male
• Biological Safety: Filter medium and housing material meet USP XXII Class VI,121 ℃

50mm diameter in-line filter:

• Housing Polypropylene
• Connector Inlet/Outlet: 7~13 mm stepped hose barb connection
• Filtration Area, ft² ≥0.021
• Maximum Operating Pressure Forward: 3.5 bar @ 23℃ and 3.0 bar @ 60℃ for liquid, 3.0 bar @ 23℃ and 2.5 bar @ 60℃ for air & gas
• Sterilization By EO, gamma or autoclave cycle of 30 min at 123℃; steam-in-place sterilization not recommended